Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
psuGIndigoidine synthase A family protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (284 aa)    
Predicted Functional Partners:
Tlet_0988
TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; KEGG: tma:TM1653 pyrimidine-nucleoside phosphorylase.
    
 0.909
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
    
  0.908
pyrR
Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.903
Tlet_1018
PFAM: purine or other phosphorylase family 1; KEGG: cpf:CPF_0375 uridine phosphorylase.
    
  0.902
Tlet_1343
PFAM: purine or other phosphorylase family 1; KEGG: tko:TK1479 uridine phosphorylase.
    
  0.902
Tlet_1428
PFAM: purine or other phosphorylase family 1; KEGG: tpe:Tpen_1240 uridine phosphorylase.
    
  0.902
Tlet_1965
PFAM: nitroreductase; KEGG: tma:TM0383 NADH oxidoreductase, putative.
       0.786
Tlet_1966
PFAM: protein of unknown function DUF6 transmembrane; KEGG: tma:TM1722 hypothetical protein.
       0.786
Tlet_1967
PFAM: regulatory protein LacI; KEGG: tma:TM0949 transcriptional regulator, LacI family.
       0.773
Tlet_1968
PFAM: peptidase membrane zinc metallopeptidase putative; KEGG: tma:TM1511 hypothetical protein.
       0.701
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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