Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tlet_1972PFAM: PhoH family protein; KEGG: tma:TM1507 phoH-related protein. (333 aa)    
Predicted Functional Partners:
ybeY
Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.987
sigA
RNA polymerase, sigma 70 subunit, RpoD family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
  
 0.845
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
     
 0.839
Tlet_1971
TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; metal-dependent phosphohydrolase 7TM intracellular region; SMART: metal-dependent phosphohydrolase HD region; KEGG: tma:TM1508 hypothetical protein.
     
 0.834
Tlet_1969
PFAM: uncharacterised conserved protein UCP033563; KEGG: tte:TTE2695 hypothetical protein.
       0.822
Tlet_1968
PFAM: peptidase membrane zinc metallopeptidase putative; KEGG: tma:TM1511 hypothetical protein.
       0.696
era
GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
 
  
 0.613
Tlet_1966
PFAM: protein of unknown function DUF6 transmembrane; KEGG: tma:TM1722 hypothetical protein.
       0.585
psuG
Indigoidine synthase A family protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.
       0.580
Tlet_1965
PFAM: nitroreductase; KEGG: tma:TM0383 NADH oxidoreductase, putative.
  
    0.576
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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