Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tlet_1987TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: tma:TM0739 hypothetical protein. (288 aa)    
Predicted Functional Partners:
Tlet_1963
TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: ttj:TTHA0989 GGDEF domain protein.
 
 0.940
Tlet_1255
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: tdn:Tmden_1336 diguanylate cyclase (GGDEF domain).
 
   0.931
thrS
threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
       0.830
Tlet_0703
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: aae:aq_035 hypothetical protein.
 
 0.664
Tlet_1870
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: rme:Rmet_6140 diguanylate cyclase/phosphodiesterase (GGDEF and EAL domains) with PAS/PAC sensor(s).
 
   0.573
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
   
   0.567
Tlet_1990
TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; KEGG: tpe:Tpen_1093 N-acetylglucosamine-6-phosphate deacetylase.
       0.548
Tlet_1989
PFAM: polysaccharide export protein; KEGG: tma:TM0638 polysaccharide export protein, putative.
       0.542
Tlet_0424
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ttj:TTHA0989 GGDEF domain protein.
 
 0.539
Tlet_1994
PFAM: flagellar protein FliS; KEGG: tma:TM1179 flagellar protein FliS.
       0.539
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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