Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tlet_1995PFAM: GCN5-related N-acetyltransferase; KEGG: tma:TM1178 acetyltransferase-related protein. (281 aa)    
Predicted Functional Partners:
Tlet_1989
PFAM: polysaccharide export protein; KEGG: tma:TM0638 polysaccharide export protein, putative.
 
    0.837
Tlet_1994
PFAM: flagellar protein FliS; KEGG: tma:TM1179 flagellar protein FliS.
       0.790
Tlet_1996
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: tpe:Tpen_1575 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
  
    0.769
Tlet_0064
PFAM: protein of unknown function DUF327; KEGG: tma:TM1646 hypothetical protein.
  
     0.765
Tlet_0055
KEGG: tma:TM1046 hypothetical protein.
 
     0.763
Tlet_1321
PFAM: protein of unknown function DUF214; KEGG: tma:TM0706 hypothetical protein.
  
    0.763
Tlet_0774
PFAM: O-antigen polymerase; KEGG: tma:TM0806 hypothetical protein.
 
     0.755
Tlet_1999
PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: tma:TM0590 penicillin-binding protein 2.
     
 0.753
Tlet_0384
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: tma:TM1359 sensor histidine kinase.
  
     0.746
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
  
  
 0.746
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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