STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xseBExodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (69 aa)    
Predicted Functional Partners:
xseA
Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.
  
 0.999
dxs
Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.855
Tlet_2012
PFAM: protein of unknown function DUF322; KEGG: tma:TM1771 hypothetical protein.
       0.827
Tlet_2011
PFAM: Dak phosphatase; KEGG: tma:TM1772 hypothetical protein.
       0.816
Tlet_2016
PFAM: DNA mismatch repair protein MutS domain protein; KEGG: fnu:FN1864 DNA mismatch repair protein MutS.
     
 0.796
Tlet_0325
PFAM: Polyprenyl synthetase; KEGG: tma:TM0161 geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
  
 0.639
Tlet_0617
TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma-70; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: tma:TM0902 RNA polymerase sigma-28 factor, putative.
    
   0.575
Tlet_2018
PFAM: UDP-glucose/GDP-mannose dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: tma:TM0583 lipopolysaccharide biosynthesis protein.
       0.575
hppA-3
V-type H(+)-translocating pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.
       0.564
Tlet_2019
PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: tma:TM0668 pleiotropic regulatory protein; Belongs to the DegT/DnrJ/EryC1 family.
       0.534
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
Server load: low (24%) [HD]