STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_2018PFAM: UDP-glucose/GDP-mannose dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: tma:TM0583 lipopolysaccharide biosynthesis protein. (434 aa)    
Predicted Functional Partners:
Tlet_0885
PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: dsy:DSY4924 hypothetical protein.
 
 
 0.997
Tlet_0884
PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: tma:TM0585 lipopolysaccharide biosynthesis protein BplA.
 
 
 0.970
Tlet_1207
PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: tma:TM0610 lipopolysaccharide biosynthesis protein.
  
 0.968
glmU
UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family.
  
 
 0.934
Tlet_2019
PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: tma:TM0668 pleiotropic regulatory protein; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.915
Tlet_2020
PFAM: regulatory protein MarR; KEGG: gme:Gmet_2889 hypothetical protein.
  
  
 0.859
hppA-3
V-type H(+)-translocating pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.
       0.706
Tlet_1906
PFAM: lipopolysaccharide biosynthesis protein; KEGG: tma:TM0644 hypothetical protein.
  
  
 0.667
Tlet_1188
PFAM: polysaccharide biosynthesis protein; KEGG: tma:TM0620 lipopolysaccharide biosynthesis protein.
 
  
 0.626
Tlet_1524
PFAM: transferase hexapeptide repeat containing protein; KEGG: tma:TM0759 acyltransferase, putative.
 
  
 0.606
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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