Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tlet_2019PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: tma:TM0668 pleiotropic regulatory protein; Belongs to the DegT/DnrJ/EryC1 family. (384 aa)    
Predicted Functional Partners:
Tlet_2020
PFAM: regulatory protein MarR; KEGG: gme:Gmet_2889 hypothetical protein.
  
  
 0.928
Tlet_2018
PFAM: UDP-glucose/GDP-mannose dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: tma:TM0583 lipopolysaccharide biosynthesis protein.
 
  
 0.915
Tlet_1006
Polysaccharide biosynthesis protein CapD; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; CoA-binding domain protein; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: tma:TM1548 lipopolysaccharide biosynthesis protein.
  
 0.855
Tlet_1524
PFAM: transferase hexapeptide repeat containing protein; KEGG: tma:TM0759 acyltransferase, putative.
   0.764
hppA-3
V-type H(+)-translocating pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.
       0.691
Tlet_0884
PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: tma:TM0585 lipopolysaccharide biosynthesis protein BplA.
  
 0.635
Tlet_2021
Citrate transporter; PFAM: Arsenical pump membrane protein; Citrate transporter; KEGG: mtp:Mthe_1347 citrate transporter.
  
  
 0.629
Tlet_0303
TIGRFAM: glucose-1-phosphate thymidyltransferase; PFAM: Nucleotidyl transferase; KEGG: tma:TM0862 glucose-1-phosphate thymidylyltransferase.
  
  
 0.619
Tlet_0392
PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: csc:Csac_1172 oxidoreductase domain protein.
  
 0.607
Tlet_1169
PFAM: sugar transferase; KEGG: tma:TM0632 extracellular polysaccharide biosynthesis-related protein.
  
 0.561
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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