STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_2027PFAM: protein of unknown function DUF369; KEGG: afu:AF2241 hypothetical protein. (124 aa)    
Predicted Functional Partners:
cobB
Silent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
       0.642
Tlet_2028
KEGG: tma:TM0491 hypothetical protein.
       0.641
Tlet_2026
PFAM: extracellular solute-binding protein family 5; KEGG: mxa:MXAN_6551 putative oligopeptide/dipeptide ABC transporter, periplasmic oligopeptide/dipeptide-binding protein.
       0.532
Tlet_2024
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sit:TM1040_2743 binding-protein-dependent transport systems inner membrane component.
       0.445
Tlet_2025
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: art:Arth_0399 binding-protein-dependent transport systems inner membrane component.
       0.445
Tlet_2022
TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: llm:llmg_1460 putative di/TRI-peptide transport ATP-binding protein; Belongs to the ABC transporter superfamily.
       0.439
Tlet_2023
TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: vvy:VVA0135 peptide ABC transporter, ATP-binding protein; Belongs to the ABC transporter superfamily.
       0.439
Tlet_2031
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
       0.415
rbsK-3
PfkB domain protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
       0.414
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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