STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
llmg_0196Prenyl transferase; Region start changed from 184692 to 184725 (-33 bases); Belongs to the FPP/GGPP synthase family. (326 aa)    
Predicted Functional Partners:
gerCA
Heptaprenyl diphosphate synthase component I; High confidence in function and specificity.
 
 
 0.995
uppS
UPP synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.980
mvaD
Diphosphomevalonate decarboxylase, GHMP kinases putative ATP-binding protein, mevDPdecarb: diphosphomevalonate decarboxylase; High confidence in function and specificity.
  
 
 0.972
ispA
Geranyltranstransferase; Farnesyltranstransferase, EC 2.5.1.29; High confidence in function and specificity; Belongs to the FPP/GGPP synthase family.
  
  
0.942
mvaA
MvaA protein; High confidence in function and specificity; Belongs to the HMG-CoA reductase family.
  
  
 0.933
menA
Prenyltransferase, UbiA family; Probable 1,4-dihydroxy-2-naphthoate octaprenyltransferase, DHNA-octaprenyltransferase, UbiA prenyltransferase; High confidence in function and specificity.
 
   
 0.929
ispB
Similar to heptaprenyl diphosphate synthase component II; High confidence in function and specificity; Belongs to the FPP/GGPP synthase family.
  
  
0.926
llmg_1583
Putative prenyltransferase; Specificity unclear.
 
  
 0.887
ubiA
Putative prenyltransferase, UbiA family; Probable 1,4-dihydroxy-2-naphthoate octaprenyltransferase; High confidence in function and specificity.
 
   
 0.877
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
  
 0.798
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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