STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
llmg_0301Transcriptional regulator, MerR family; Family membership. (122 aa)    
Predicted Functional Partners:
llmg_0300
Hypothetical protein predicted by Glimmer/Critica.
       0.662
llmg_0572
HTH-type transcriptional regulator, Putative DNA binding; Family membership.
  
     0.612
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.568
rmeD
Transcriptional regulator, MerR family; Putative DNA binding; Conserved hypothetical protein.
  
     0.530
llmg_0304
Conserved hypothetical protein; Protein of unknown function DUF1447; Belongs to the UPF0356 family.
   
   0.522
rnj
Putative Zn-dependent hydrolase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
   
   0.515
glnA
GlnA protein; PF00120: Glutamine synthetase, catalytic domain, TIGR00653: glutamine synthetase, type I; High confidence in function and specificity.
  
 
 0.479
rpoD
RNA polymerase sigma factor rpoD (Sigma-42); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.442
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.428
rpoA
RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.418
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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