STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
napCMultidrug-efflux transporter protein; Putative tetracycline resistance protein; High confidence in function and specificity. (396 aa)    
Predicted Functional Partners:
lmrA
Multidrug resistance ABC transporter ATP-binding and permease protein; Efflux transporter for a variety of amphiphilic cationic compounds, including antibiotics; Belongs to the ABC transporter superfamily. Multidrug exporter LmrA (TC 3.A.1.117.1) family.
      
 0.900
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
      0.834
pepN
PepN protein; Aminopeptidase with broad substrate specificity to several peptides. It has more affinity for oligopeptides than for dipeptides. It plays an essential role in the metabolism, it may be involved in nitrogen supply or protein turnover.
      
 0.551
aroD
Putative 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
     
 0.469
dltE
Oxidoreductase dltE; 3-oxoacyl-[acyl-carrier-protein] reductase, Short-chain dehydrogenase/reductase SDR, Fatty acid biosynthesis pathway; High confidence in function and specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
      0.462
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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