STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nifZPyridoxal-phosphate dependent aminotransferase; Aminotransferase class-V; High confidence in function and specificity. (381 aa)    
Predicted Functional Partners:
thiI
Thiamine biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
 0.994
nifU
Conserved hypothetical protein; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
 
 0.934
nifS
Putative iron-sulfur cofactor synthesis protein; Cysteine desulfurase/Cysteine sulfinate desulfinase; High confidence in function and specificity.
  
  
 
0.918
hdiR
HTH-type transcriptional regulator HdiR; IPR011056: Peptidase S24 and S26, C-terminal region, PF01381: Helix-turn-helix; Conserved hypothetical protein.
      
 0.776
snf
SWI/SNF family helicase; PF00176:SNF2 family N-terminal domain; Family membership.
   
 
 0.682
llmg_2049
Conserved hypothetical protein.
  
 
 0.625
tmcAL
Putative nucleotidyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
  
   
 0.602
llmg_1972
Conserved hypothetical protein; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
    
0.582
birA1
biotin--[acetyl-CoA-carboxylase] ligase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.562
dnaK
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
  
 0.558
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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