STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ponAPutative penicillin-binding protein 1a; Includes: Penicillin- insensitive transglycosylase (EC 2.4.2.-) (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (EC 3.4.-.-) (DD-transpeptidase)]., PBP_1a_fam: penicillin-binding protein, 1A family; High confidence in function and specificity. (693 aa)    
Predicted Functional Partners:
pbpX
Penicillin-binding protein; High confidence in function and specificity.
 
 
 0.986
pbp2B
Penicillin-binding protein 2B; High confidence in function and specificity.
 
 
 0.979
dacA
DacA protein; D-alanyl-D-alanine carboxypeptidase precursor, PF00768: D-alanyl-D-alanine carboxypeptidase; High confidence in function and specificity; Belongs to the peptidase S11 family.
 
 
 0.932
pbp1B
Penicillin-binding protein 1B; High confidence in function and specificity.
  
  
0.930
pbp2A
Penicillin-binding protein 2a; PF00912: Transglycosylase; High confidence in function and specificity.
  
  
 
0.927
dacB
DacB protein; High confidence in function and specificity.
     
 0.902
recU
Putative recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
  
 0.867
acmA
N-acetylglucosaminidase; Hydrolyzes the cell wall of L.lactis and M.lysodeikticus. Required for cell separation during growth; Belongs to the glycosyl hydrolase 73 family.
 
  
 0.836
llmg_0510
Putative Zn-dependent hydrolase of metallo-beta-lactamase superfamily; Metallo-beta-lactamase superfamily; Family membership.
       0.779
rodA
Rod shape-determining protein RodA; Cell cycle protein; High confidence in function and specificity; Belongs to the SEDS family.
  
 
 
 0.760
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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