node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
clpX | dapA | llmg_1340 | llmg_0874 | ATP-dependent Clp protease ATP-binding subunit clpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.504 |
clpX | spxA | llmg_1340 | llmg_0514 | ATP-dependent Clp protease ATP-binding subunit clpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Conserved hypothetical protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | 0.494 |
clpX | trxA | llmg_1340 | llmg_0779 | ATP-dependent Clp protease ATP-binding subunit clpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Contains thioredoxin domain 2; High confidence in function and specificity; Belongs to the thioredoxin family. | 0.448 |
dapA | clpX | llmg_0874 | llmg_1340 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | ATP-dependent Clp protease ATP-binding subunit clpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.504 |
dapA | spxA | llmg_0874 | llmg_0514 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Conserved hypothetical protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | 0.552 |
llmg_1768 | spxA | llmg_1768 | llmg_0514 | Conserved hypothetical protein; Similar to regulatory protein spx; Family membership; Belongs to the ArsC family. | Conserved hypothetical protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | 0.639 |
msrA | osmC | llmg_0951 | llmg_0080 | MsrA protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | OsmC-like protein; High confidence in function and specificity. | 0.565 |
msrA | spxA | llmg_0951 | llmg_0514 | MsrA protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Conserved hypothetical protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | 0.663 |
msrA | trxA | llmg_0951 | llmg_0779 | MsrA protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Contains thioredoxin domain 2; High confidence in function and specificity; Belongs to the thioredoxin family. | 0.540 |
osmC | msrA | llmg_0080 | llmg_0951 | OsmC-like protein; High confidence in function and specificity. | MsrA protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.565 |
osmC | pmsR | llmg_0080 | llmg_2281 | OsmC-like protein; High confidence in function and specificity. | PmsR protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.565 |
osmC | potD | llmg_0080 | llmg_1325 | OsmC-like protein; High confidence in function and specificity. | Spermidine/putrescine ABC transporter substrate binding; High confidence in function and specificity. | 0.623 |
osmC | scpB | llmg_0080 | llmg_1193 | OsmC-like protein; High confidence in function and specificity. | Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | 0.580 |
osmC | spxA | llmg_0080 | llmg_0514 | OsmC-like protein; High confidence in function and specificity. | Conserved hypothetical protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | 0.498 |
pmsR | osmC | llmg_2281 | llmg_0080 | PmsR protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | OsmC-like protein; High confidence in function and specificity. | 0.565 |
pmsR | spxA | llmg_2281 | llmg_0514 | PmsR protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Conserved hypothetical protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | 0.642 |
pmsR | trxA | llmg_2281 | llmg_0779 | PmsR protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Contains thioredoxin domain 2; High confidence in function and specificity; Belongs to the thioredoxin family. | 0.539 |
potD | osmC | llmg_1325 | llmg_0080 | Spermidine/putrescine ABC transporter substrate binding; High confidence in function and specificity. | OsmC-like protein; High confidence in function and specificity. | 0.623 |
potD | scpB | llmg_1325 | llmg_1193 | Spermidine/putrescine ABC transporter substrate binding; High confidence in function and specificity. | Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | 0.775 |
potD | spxA | llmg_1325 | llmg_0514 | Spermidine/putrescine ABC transporter substrate binding; High confidence in function and specificity. | Conserved hypothetical protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily. | 0.565 |