STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dfpBPutative phosphopantothenate--cysteine ligase; (Phosphopantothenoylcysteine synthetase) (PPC synthetase); High confidence in function and specificity. (231 aa)    
Predicted Functional Partners:
dfpA
Putative DNA/pantothenate metabolism flavoprotein; Putative phosphopantothenoylcysteine decarboxylase; High confidence in function and specificity.
 
 0.999
coaA
Pantothenate kinase; High confidence in function and specificity.
   
 
 0.916
panT
Putative membrane protein; Probably a pantothenic acid-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins.
 
     0.854
llmg_0508
Cysteine synthase; Unnamed protein product; Region start changed from 500979 to 500913 (-66 bases); Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.806
cysK
O-acetylserine sulfhydrylase; Cysteine synthase; High confidence in function and specificity; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.806
metC
Cystathionine beta-lyase; The enzymatic degradation of amino acids in cheese is believed to generate aroma compounds and therefore to be essential for flavor development. Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine but is also able to catalyze an alpha, gamma elimination. With methionine as a substrate, it produces volatile sulfur compounds which are important for flavor formation in Gouda cheese; Belongs to the trans-sulfuration enzymes family.
   
 
  0.804
priA
Primosomal protein N' (Replication factor Y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
 
    0.553
pgmA
Alpha-phosphoglucomutase; HAD-SF-IIB: HAD-superfamily hydrolase, subfamily IIB; High confidence in function and specificity.
       0.512
xylH
[EC:5.3.2.-], 4-oxalocrotonate tautomerase, Tautomerase enzyme; Conserved hypothetical protein.
  
    0.492
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
  
  
 0.460
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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