STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
brnQBranched-chain amino acid transport system II carrier protein; Component of the transport system for branched-chain amino acids. Can transport isoleucine, leucine and valine. (449 aa)    
Predicted Functional Partners:
dapD
2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
  
  
 0.748
ctrA
Putative amino-acid transporter; Amino acid permease-associated region, COG: Amino acid transporters, PFAM: Amino acid permease, 2A0306: amino acid transporter; Conserved hypothetical protein.
     
 0.735
metE2
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; High confidence in function and specificity.
   
  
 0.727
codY
Transcriptional regulator; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
      
 0.720
thrC
ThrC protein; TIGR00260: threonine synthase; High confidence in function and specificity.
 
   
 0.651
gltQ
Glutamate ABC transporter ATP binding protein; Conserved hypothetical protein.
      
 0.623
thrB
ThrB protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
   
 0.590
dppA
Dipeptide-binding protein precursor.
      
 0.518
gatA
Amidase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
      
 0.517
oppA
Oligopeptide-binding protein oppA precursor; Bacterial extracellular solute-binding protein, family 5; High confidence in function and specificity.
     
 0.483
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.