STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kinFSensor protein kinase kinF; Histidine kinase; High confidence in function and specificity. (456 aa)    
Predicted Functional Partners:
llrF
Two-component system regulator llrF; Response regulator receiver domain; High confidence in function and specificity.
 0.999
zitS
Zinc ABC transporter substrate binding protein; PF01297.7: Periplasmic solute binding protein family; High confidence in function and specificity; Belongs to the bacterial solute-binding protein 9 family.
   
  
 0.960
llrA
Two-component system regulator llrA; Contains response regulator receiver domain; High confidence in function and specificity.
 
 0.903
llrB
Two-component system regulator llrB; Response regulator receiver domain; High confidence in function and specificity.
 
 0.892
llrC
Two-component system regulator; Response regulator receiver domain, PhoB: Phosphate regulon transcriptional regulatory protein phoB; Conserved hypothetical protein.
 
 0.891
llrE
Two-component system regulator llrE; Response regulator receiver domain; High confidence in function and specificity.
 
 0.890
llrG
Response regulator; Conserved hypothetical protein.
 
 0.792
pdhC
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, PDHac_trf_long: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; High confidence in function and specificity.
    
 0.551
rbsB
Ribose ABC transporter substrate binding protein RbsB; High confidence in function and specificity.
 
  
 
 0.538
htrA
Housekeeping protease; Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock, ethanol, puromycin and NaCl) resistance during active exponential growth (By similarity); Belongs to the peptidase S1C family.
  
 0.520
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.