STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ftsKDNA translocase ftsK; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the difSL recombination site, which is located within the replication terminus region (By similarity). Required for activation of the XerS recombinase, allowing activation of chromosome unlinking by recombination; Belongs to the FtsK/SpoIIIE/SftA family. (755 aa)    
Predicted Functional Partners:
xerD
Integrase-recombinase; DNA breaking-rejoining enzyme, catalytic core, Phage integrase family; Conserved hypothetical protein; Belongs to the 'phage' integrase family.
  
   
 0.986
xerD-2
Putative integrase/recombinase; Similar to phage integrase family proteins; High confidence in function and specificity; Belongs to the 'phage' integrase family.
  
   
 0.983
ftsZ
Cell division protein ftsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.949
ceo2
Pseudogene; N5-carboxyethyl-ornithine synthase, PF01262: Alanine dehydrogenase/PNT, C-terminal domain, possible pseudogene; High confidence in function and specificity; Belongs to the 'phage' integrase family.
  
   
 0.941
xerS
Tyrosine recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. Binds an atypical recombination dif site (difSL). Binds preferentially to the left arm and cooperatively to the right arm of difSL ; Belongs to the 'phage' integrase family. XerS subfamily.
  
   
 0.928
ps334
TIGR01547: phage terminase, large subunit, PBSX family.
   
  
 0.880
ftsA
Cell division protein ftsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
  
  
 0.845
pbp2B
Penicillin-binding protein 2B; High confidence in function and specificity.
 
 
 0.838
ftsQ
Cell division protein ftsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
   
 
 0.823
llmg_1968
Uncharacterized protein conserved in bacteria; Belongs to the WXG100 family.
  
 
 0.809
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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