STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
llmg_0771Putative N6-adenine-specific DNA methylase; Family membership; Belongs to the methyltransferase superfamily. (384 aa)    
Predicted Functional Partners:
llmg_0263
Putative methyltransferase; PS50193: contains SAM (and some other nucleotide) binding motif; Family membership.
 
  
 0.929
argS
ArgS protein; PF00750: tRNA synthetases class I, TIGR00456: arginyl-tRNA synthetase; High confidence in function and specificity.
 
    0.557
llmg_1175
Conserved hypothetical protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
  
  
 0.540
mapZ
Conserved hypothetical protein; Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning.
       0.520
uppS
UPP synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
   
    0.518
pnpA
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
    0.495
exoA
3'-exo-deoxyribonuclease; Exodeoxyribonuclease A; High confidence in function and specificity.
  
    0.461
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Is essential for the synthesis of CTP de novo. Contrary to other bacterial CTP synthases, the lactococcal enzyme is also able to convert dUTP to dCTP, but this reaction may not play a significant physiological role. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates (By similarity).
  
    0.459
thiI
Thiamine biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
  
 0.449
llmg_0231
Conserved hypothetical protein; Region start changed from 222123 to 222183 (-60 bases).
  
  
 0.448
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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