STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lplASugar ABC transporter substrate-binding protein; High confidence in function and specificity. (398 aa)    
Predicted Functional Partners:
lplB
Sugar ABC transporter substrate binding protein; High confidence in function and specificity.
 
 0.991
lplC
Sugar ABC transporter permease.
 
 0.991
llmg_1012
Putative ABC transporter substrate-binding protein; Specificity unclear.
     0.991
llmg_1839
Putative sugar ABC transporter permease; Family membership.
 
 0.978
llmg_1838
Putative sugar ABC transporter substrate-binding protein; Family membership.
  
  
 
0.929
bioY
Putative biotin synthase; Probably a biotin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins.
      
 0.904
birA1
biotin--[acetyl-CoA-carboxylase] ligase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.794
birA2
acetyl-CoA carboxylase ligase / biotin operon repressor bifunctional protein; BirA bifunctional protein; High confidence in function and specificity.
     
 0.759
msmK
Probable multiple sugar-binding transport ATP-binding protein; Conserved hypothetical protein; Belongs to the ABC transporter superfamily.
  
 
 0.742
aguA
AguA protein; PF07488: Glycosyl hydrolase family 67 middle domain, PF07477: Glycosyl hydrolase family 67 C-terminus; High confidence in function and specificity.
 
     0.738
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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