STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
furPseudogene; Transposase for insertion sequence element IS905E, contains a stop codon at position 606; High confidence in function and specificity; Belongs to the Fur family. (128 aa)    
Predicted Functional Partners:
xerD
Integrase-recombinase; DNA breaking-rejoining enzyme, catalytic core, Phage integrase family; Conserved hypothetical protein; Belongs to the 'phage' integrase family.
     
 0.926
xerD-2
Putative integrase/recombinase; Similar to phage integrase family proteins; High confidence in function and specificity; Belongs to the 'phage' integrase family.
     
 0.926
ahpC
Alkyl hydroperoxide reductase subunit C; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
  
 0.681
rpoD
RNA polymerase sigma factor rpoD (Sigma-42); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.668
llmg_1224
Transcriptional regulator; PF01325: Iron dependent repressor, N-terminal DNA binding domain; Conserved hypothetical protein.
  
  
 0.621
zitQ
Zinc ABC transporter ATP binding protein; PF00005: ABC transporter; High confidence in function and specificity.
  
  
 0.611
trxA
Contains thioredoxin domain 2; High confidence in function and specificity; Belongs to the thioredoxin family.
  
 
 0.591
rpoA
RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.565
llmg_1025
Conserved hypothetical protein; Protein of unknown function DUF125.
     
 0.560
llmg_1024
Integral membrane protein DUF125; Conserved hypothetical protein.
     
 0.559
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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