Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| glyA | ilvA | llmg_0563 | llmg_1276 | GlyA protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | IlvA protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.926 |
| glyA | sdaA | llmg_0563 | llmg_1732 | GlyA protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-serine dehydratase alpha subunit; High confidence in function and specificity; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.976 |
| glyA | trpA | llmg_0563 | llmg_1042 | GlyA protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | TrpA protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.932 |
| glyA | trpB | llmg_0563 | llmg_1041 | GlyA protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | TrpB protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.926 |
| ilvA | glyA | llmg_1276 | llmg_0563 | IlvA protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | GlyA protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.926 |
| ilvA | sdaA | llmg_1276 | llmg_1732 | IlvA protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | L-serine dehydratase alpha subunit; High confidence in function and specificity; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.940 |
| ilvA | trpA | llmg_1276 | llmg_1042 | IlvA protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | TrpA protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.926 |
| ilvA | trpB | llmg_1276 | llmg_1041 | IlvA protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | TrpB protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.942 |
| pabA | trpA | llmg_1153 | llmg_1042 | P-aminobenzoate synthetase, component II; PF00117: Glutamine amidotransferase class-I, TIGR00566: glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase; High confidence in function and specificity. | TrpA protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.917 |
| pabA | trpB | llmg_1153 | llmg_1041 | P-aminobenzoate synthetase, component II; PF00117: Glutamine amidotransferase class-I, TIGR00566: glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase; High confidence in function and specificity. | TrpB protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.853 |
| pabA | trpC | llmg_1153 | llmg_1038 | P-aminobenzoate synthetase, component II; PF00117: Glutamine amidotransferase class-I, TIGR00566: glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase; High confidence in function and specificity. | TrpC protein; High confidence in function and specificity; Belongs to the TrpC family. | 0.994 |
| pabA | trpD | llmg_1153 | llmg_1032 | P-aminobenzoate synthetase, component II; PF00117: Glutamine amidotransferase class-I, TIGR00566: glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase; High confidence in function and specificity. | TrpD protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.993 |
| pabA | trpE | llmg_1153 | llmg_1030 | P-aminobenzoate synthetase, component II; PF00117: Glutamine amidotransferase class-I, TIGR00566: glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase; High confidence in function and specificity. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |
| pabA | trpF | llmg_1153 | llmg_1039 | P-aminobenzoate synthetase, component II; PF00117: Glutamine amidotransferase class-I, TIGR00566: glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase; High confidence in function and specificity. | N-(5'-phosphoribosyl)-anthranilate isomerase; High confidence in function and specificity; Belongs to the TrpF family. | 0.986 |
| pabA | trpG | llmg_1153 | llmg_1031 | P-aminobenzoate synthetase, component II; PF00117: Glutamine amidotransferase class-I, TIGR00566: glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase; High confidence in function and specificity. | Anthranilate synthase component II; High confidence in function and specificity. | 0.820 |
| sdaA | glyA | llmg_1732 | llmg_0563 | L-serine dehydratase alpha subunit; High confidence in function and specificity; Belongs to the iron-sulfur dependent L-serine dehydratase family. | GlyA protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.976 |
| sdaA | ilvA | llmg_1732 | llmg_1276 | L-serine dehydratase alpha subunit; High confidence in function and specificity; Belongs to the iron-sulfur dependent L-serine dehydratase family. | IlvA protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.940 |
| sdaA | trpA | llmg_1732 | llmg_1042 | L-serine dehydratase alpha subunit; High confidence in function and specificity; Belongs to the iron-sulfur dependent L-serine dehydratase family. | TrpA protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.904 |
| sdaA | trpB | llmg_1732 | llmg_1041 | L-serine dehydratase alpha subunit; High confidence in function and specificity; Belongs to the iron-sulfur dependent L-serine dehydratase family. | TrpB protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
| trpA | glyA | llmg_1042 | llmg_0563 | TrpA protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | GlyA protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.932 |
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