STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gadCPutative glutamate/gamma-aminobutyrate antiporter; Involved in glutamate-dependent acid resistance. May be involved in antiport of glutamate and glutamate-gamma-aminobutyrate (GABA). (504 aa)    
Predicted Functional Partners:
gadB
Glutamate decarboxylase; Converts internalized glutamate to GABA and increases the internal pH. Involved in glutamate-dependent acid resistance; Belongs to the group II decarboxylase family.
 
  
 0.997
gadR
Positive regulator GadR; Activates chloride dependent transcription of gadCB, TIGR01716: Transcriptional activator Rgg/GadR/MutR, C-terminal domain; High confidence in function and specificity.
     
 0.978
arcA
ArcA protein; PF02274: Amidinotransferase, TIGR01078: arginine deiminase; High confidence in function and specificity.
  
  
 0.770
llmg_1747
Amino acid permease; Family membership.
   
  
 0.698
serP1
Amino acid permease; Transports L-serine, L-threonine and L-cysteine with high affinity. Stereoselective, with a strong preference for L-serine. Is the main L-serine transporter and is responsible for optimal growth in media containing free amino acids as the sole source of amino acids. Is also the main transporter for L- threonine ; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
   
  
 0.564
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
  
  
 0.559
gltB
Glutamate synthase, large subunit; PF01645: Conserved region in glutamate synthase; High confidence in function and specificity.
  
  
 0.552
rny
Hypothetical protein; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
      
 0.482
serP2
Amino acid permease; Transports DL-alanine, DL-serine and glycine. The preferred substrate is DL- alanine. L-serine is a low-affinity substrate. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
   
  
 0.475
dexC
Neopullulanase; Cyclomaltodextrinase; High confidence in function and specificity; Belongs to the glycosyl hydrolase 13 family.
   
 0.468
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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