Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ceoN5-carboxyethyl-ornithine synthase; High confidence in function and specificity. (312 aa)    
Predicted Functional Partners:
scrK
Fructokinase; High confidence in function and specificity.
      
 0.850
alr
Alr protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.
  
  
 0.759
gltB
Glutamate synthase, large subunit; PF01645: Conserved region in glutamate synthase; High confidence in function and specificity.
      
 0.557
nifJ
NifJ protein; Pyruvate:ferredoxin (flavodoxin) oxidoreductase, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain, pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase; High confidence in function and specificity.
     
 0.520
adhE
PF00465.7: Iron-containing alcohol dehydrogenase; High confidence in function and specificity; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
     
 0.479
ilvA
IlvA protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
     
 0.412
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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