STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fruAPseudogene; Transposase for insertion sequence IS1077F (fragment); High confidence in function and specificity. (634 aa)    
Predicted Functional Partners:
mtlF
PTS system, mannitol-specific IIABC component (EIIABC-Mtl), Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; High confidence in function and specificity.
 
  
 0.999
fruC
Fructose 1-phosphate kinase; High confidence in function and specificity; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 0.999
ptsH
Phosphocarrier protein HPr (Histidine-containing protein)., PTS HPr component phosphorylation site, PTS_HPr_family: phosphocarrier protein HPr; High confidence in function and specificity.
 
 
 0.997
bglP
Pseudogene; 3' end of bglR, Interrupted by insertion element; Conserved hypothetical protein.
 
  
 0.997
llmg_1426
Sucrose-specific PTS system IIBC component; High confidence in function and specificity.
 
  
 0.991
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.988
fruR
Transcriptional regulator of the fructose operon; Bacterial regulatory proteins, deoR family; High confidence in function and specificity.
 
  
 0.966
fbaA
Pseudogene; Transposase for insertion sequence element IS905M, contains a stop codon at position 606; Conserved hypothetical protein.
  
 
 0.964
scrK
Fructokinase; High confidence in function and specificity.
  
 
 0.946
xylA
XylA protein; High confidence in function and specificity.
   
 
 0.944
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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