STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mleSMalolactic enzyme; High confidence in function and specificity. (540 aa)    
Predicted Functional Partners:
mleP
Malate transporter; High confidence in function and specificity.
 
  
 0.989
mleR
Pseudogene; Transposase for insertion sequence element IS905J, contains a frameshift at position 401; Conserved hypothetical protein; Belongs to the LysR transcriptional regulatory family.
 
 
 
 0.944
ldhB
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.930
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.930
ldhX
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.930
llmg_0475
Malate/lactate dehydrogenase; Similar to ldhB; Specificity unclear; Belongs to the LDH/MDH superfamily.
  
 0.923
gltA
GltA protein; cit_synth_II: 2-methylcitrate synthase/citrate synthase II; High confidence in function and specificity; Belongs to the citrate synthase family.
  
 0.895
llmg_2184
Conserved hypothetical protein; Predicted permeases.
  
  
 0.750
nifJ
NifJ protein; Pyruvate:ferredoxin (flavodoxin) oxidoreductase, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain, pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase; High confidence in function and specificity.
  
  
 0.679
dar
Acetoin(diacetyl)reductase; High confidence in function and specificity.
   
 
 0.573
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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