node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dnaA | hslB | llmg_0001 | llmg_1661 | Replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Histone-like bacterial DNA-binding protein; High confidence in function and specificity. | 0.560 |
greA | hslB | llmg_0610 | llmg_1661 | Transcription elongation factor greA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. | Histone-like bacterial DNA-binding protein; High confidence in function and specificity. | 0.553 |
greA | metS | llmg_0610 | llmg_1764 | Transcription elongation factor greA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. | MetS protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.427 |
greA | rheA | llmg_0610 | llmg_0369 | Transcription elongation factor greA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. | ATP-dependent RNA helicase; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily. | 0.615 |
greA | rheB | llmg_0610 | llmg_0433 | Transcription elongation factor greA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. | ATP-dependent RNA helicase; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. | 0.472 |
hslB | dnaA | llmg_1661 | llmg_0001 | Histone-like bacterial DNA-binding protein; High confidence in function and specificity. | Replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.560 |
hslB | greA | llmg_1661 | llmg_0610 | Histone-like bacterial DNA-binding protein; High confidence in function and specificity. | Transcription elongation factor greA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. | 0.553 |
hslB | llmg_0507 | llmg_1661 | llmg_0507 | Histone-like bacterial DNA-binding protein; High confidence in function and specificity. | Peptide binding protein; Similar to oligopeptide ABC transporter substrate binding proteins; Conserved hypothetical protein. | 0.758 |
hslB | metS | llmg_1661 | llmg_1764 | Histone-like bacterial DNA-binding protein; High confidence in function and specificity. | MetS protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.472 |
hslB | rheA | llmg_1661 | llmg_0369 | Histone-like bacterial DNA-binding protein; High confidence in function and specificity. | ATP-dependent RNA helicase; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily. | 0.776 |
hslB | rheB | llmg_1661 | llmg_0433 | Histone-like bacterial DNA-binding protein; High confidence in function and specificity. | ATP-dependent RNA helicase; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. | 0.718 |
hslB | rplU | llmg_1661 | llmg_1493 | Histone-like bacterial DNA-binding protein; High confidence in function and specificity. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.522 |
hslB | rpmF | llmg_1661 | llmg_0099 | Histone-like bacterial DNA-binding protein; High confidence in function and specificity. | Ribosomal L32p protein; High confidence in function and specificity; Belongs to the bacterial ribosomal protein bL32 family. | 0.463 |
hslB | rpsT | llmg_1661 | llmg_1921 | Histone-like bacterial DNA-binding protein; High confidence in function and specificity. | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.517 |
hslB | topA | llmg_1661 | llmg_1272 | Histone-like bacterial DNA-binding protein; High confidence in function and specificity. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.469 |
llmg_0507 | hslB | llmg_0507 | llmg_1661 | Peptide binding protein; Similar to oligopeptide ABC transporter substrate binding proteins; Conserved hypothetical protein. | Histone-like bacterial DNA-binding protein; High confidence in function and specificity. | 0.758 |
metS | greA | llmg_1764 | llmg_0610 | MetS protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | Transcription elongation factor greA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. | 0.427 |
metS | hslB | llmg_1764 | llmg_1661 | MetS protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | Histone-like bacterial DNA-binding protein; High confidence in function and specificity. | 0.472 |
metS | rpmF | llmg_1764 | llmg_0099 | MetS protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | Ribosomal L32p protein; High confidence in function and specificity; Belongs to the bacterial ribosomal protein bL32 family. | 0.467 |
metS | topA | llmg_1764 | llmg_1272 | MetS protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.675 |