STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
llmg_1768Conserved hypothetical protein; Similar to regulatory protein spx; Family membership; Belongs to the ArsC family. (116 aa)    
Predicted Functional Partners:
llmg_1513
arsC_related: conserved hypothetical protein, Similar to Regulatory protein spx.
  
   
 0.693
trmA
Regulatory protein spx; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity). Belongs to the ArsC family. Spx subfamily.
  
   
 0.659
spxA
Conserved hypothetical protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.
  
   
 0.639
llmg_1769
Conserved hypothetical protein; Protein of unknown function DUF156.
       0.565
noxC
NADH oxidase; High confidence in function and specificity.
     
 0.534
llmg_1771
Putative rhodanese-related sulfurtransferase; Contains rhodanese-like domain; Conserved hypothetical protein.
       0.511
llmg_1772
Putative rhodanese-related sulfurtransferase; Contains Rhodanese-like domain; Conserved hypothetical protein.
       0.507
llmg_1773
Conserved hypothetical protein; CsbD-like protein; Belongs to the UPF0337 (CsbD) family.
  
    0.468
rpoA
RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.418
llmg_1774
Hypothetical protein predicted by Glimmer/Critica.
       0.408
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.