STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
llmg_2280Conserved hypothetical protein; PF06855: Protein of unknown function DUF1250; Belongs to the UPF0346 family. (69 aa)    
Predicted Functional Partners:
pmsR
PmsR protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
       0.707
llmg_0493
Putative esterase/lipase; PF00657.10: GDSL-like Lipase/Acylhydrolase; Family membership.
 
  
 0.681
llmg_0495
Uncharacterized protein conserved in bacteria.
 
   
 0.665
llmg_1310
Conserved hypothetical protein; TPR domain protein.
  
     0.596
llmg_2278
Hypothetical protein predicted by Glimmer/Critica; Putative membrane protein.
       0.581
bcrA
Putative bacitracin transport ATP-binding protein; PF00005: ABC transporter; Conserved hypothetical protein.
       0.581
llmg_0769
Putative DivIVA cell division initiation protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
  
     0.536
llmg_2282
Conserved hypothetical protein; IPR008994: Nucleic acid-binding, OB-fold; Belongs to the CvfB family.
     
 0.487
llmg_1751
Alkaline phosphatase superfamily protein.
  
     0.426
ezrA
Septation ring formation regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
    0.425
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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