llmg_2330 protein (Lactococcus lactis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

llmg_2330

Probable amino-acid ABC transporter extracellular binding protein; PF00497: Bacterial extracellular solute-binding protein, family 3; Family membership. (280 aa)

Predicted Functional Partners:

llmg_1591

0.971

rpsR

0.906

llmg_1590

0.781

gltP

0.775

dltD

0.753

glnQ

0.716

gltQ

0.700

ogt

0.664

lrgA

0.600

llmg_2329

0.582

Your Current Organism:

Lactococcus lactis

NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
dltD	llmg_2330	llmg_1222	llmg_2330	D-alanine transfer protein DltD; PF04918: DltD central region; High confidence in function and specificity.	Probable amino-acid ABC transporter extracellular binding protein; PF00497: Bacterial extracellular solute-binding protein, family 3; Family membership.	0.753
glnQ	gltP	llmg_1943	llmg_1979	Glutamine ABC transporter ATP-binding protein; High confidence in function and specificity.	Amino acid ABC transporter permease protein; High confidence in function and specificity.	0.975
glnQ	llmg_1591	llmg_1943	llmg_1591	Glutamine ABC transporter ATP-binding protein; High confidence in function and specificity.	Putative amino-acid ABC transporter permease protein; Specificity unclear.	0.947
glnQ	llmg_2330	llmg_1943	llmg_2330	Glutamine ABC transporter ATP-binding protein; High confidence in function and specificity.	Probable amino-acid ABC transporter extracellular binding protein; PF00497: Bacterial extracellular solute-binding protein, family 3; Family membership.	0.716
gltP	glnQ	llmg_1979	llmg_1943	Amino acid ABC transporter permease protein; High confidence in function and specificity.	Glutamine ABC transporter ATP-binding protein; High confidence in function and specificity.	0.975
gltP	gltQ	llmg_1979	llmg_1978	Amino acid ABC transporter permease protein; High confidence in function and specificity.	Glutamate ABC transporter ATP binding protein; Conserved hypothetical protein.	0.999
gltP	llmg_1590	llmg_1979	llmg_1590	Amino acid ABC transporter permease protein; High confidence in function and specificity.	Putative amino-acid ABC transporter ATP-binding protein; Specificity unclear.	0.983
gltP	llmg_1591	llmg_1979	llmg_1591	Amino acid ABC transporter permease protein; High confidence in function and specificity.	Putative amino-acid ABC transporter permease protein; Specificity unclear.	0.571
gltP	llmg_2330	llmg_1979	llmg_2330	Amino acid ABC transporter permease protein; High confidence in function and specificity.	Probable amino-acid ABC transporter extracellular binding protein; PF00497: Bacterial extracellular solute-binding protein, family 3; Family membership.	0.775
gltQ	gltP	llmg_1978	llmg_1979	Glutamate ABC transporter ATP binding protein; Conserved hypothetical protein.	Amino acid ABC transporter permease protein; High confidence in function and specificity.	0.999
gltQ	llmg_1591	llmg_1978	llmg_1591	Glutamate ABC transporter ATP binding protein; Conserved hypothetical protein.	Putative amino-acid ABC transporter permease protein; Specificity unclear.	0.945
gltQ	llmg_2330	llmg_1978	llmg_2330	Glutamate ABC transporter ATP binding protein; Conserved hypothetical protein.	Probable amino-acid ABC transporter extracellular binding protein; PF00497: Bacterial extracellular solute-binding protein, family 3; Family membership.	0.700
llmg_1590	gltP	llmg_1590	llmg_1979	Putative amino-acid ABC transporter ATP-binding protein; Specificity unclear.	Amino acid ABC transporter permease protein; High confidence in function and specificity.	0.983
llmg_1590	llmg_1591	llmg_1590	llmg_1591	Putative amino-acid ABC transporter ATP-binding protein; Specificity unclear.	Putative amino-acid ABC transporter permease protein; Specificity unclear.	0.999
llmg_1590	llmg_2330	llmg_1590	llmg_2330	Putative amino-acid ABC transporter ATP-binding protein; Specificity unclear.	Probable amino-acid ABC transporter extracellular binding protein; PF00497: Bacterial extracellular solute-binding protein, family 3; Family membership.	0.781
llmg_1591	glnQ	llmg_1591	llmg_1943	Putative amino-acid ABC transporter permease protein; Specificity unclear.	Glutamine ABC transporter ATP-binding protein; High confidence in function and specificity.	0.947
llmg_1591	gltP	llmg_1591	llmg_1979	Putative amino-acid ABC transporter permease protein; Specificity unclear.	Amino acid ABC transporter permease protein; High confidence in function and specificity.	0.571
llmg_1591	gltQ	llmg_1591	llmg_1978	Putative amino-acid ABC transporter permease protein; Specificity unclear.	Glutamate ABC transporter ATP binding protein; Conserved hypothetical protein.	0.945
llmg_1591	llmg_1590	llmg_1591	llmg_1590	Putative amino-acid ABC transporter permease protein; Specificity unclear.	Putative amino-acid ABC transporter ATP-binding protein; Specificity unclear.	0.999
llmg_1591	llmg_2330	llmg_1591	llmg_2330	Putative amino-acid ABC transporter permease protein; Specificity unclear.	Probable amino-acid ABC transporter extracellular binding protein; PF00497: Bacterial extracellular solute-binding protein, family 3; Family membership.	0.971

page 1 of 2

Network Stats

number of nodes:

3

number of edges:

3

average node degree:

2

avg. local clustering coefficient:

1

expected number of edges:

2

PPI enrichment p-value:

0.211

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:37756079

(2023) Conserved Domains in Variable Surface Lipoproteins A-G of Mycoplasma hyorhinis May Serve as Probable Multi-Epitope Candidate Vaccine: Computational Reverse Vaccinology Approach.

3 of 5

2.14

3.09

5.49e-05

PMID:27738034

(2016) Genome Sequence of Mycoplasma hyorhinis Isolated from Cell Cultures.

3 of 5

2.14

3.09

5.49e-05

PMID:23405353

(2013) Complete Genome Sequence of Mycoplasma hyorhinis Strain SK76.

3 of 5

2.14

3.09

5.49e-05

PMID:31589633

(2019) Early detection and differential serodiagnosis of Mycoplasma hyorhinis and Mycoplasma hyosynoviae infections under experimental conditions.

3 of 7

2.0

2.9

5.49e-05

PMID:31324222

(2019) Tn-sequencing of Mycoplasma hyopneumoniae and Mycoplasma hyorhinis mutant libraries reveals non-essential genes of porcine mycoplasmas differing in pathogenicity.

3 of 14

1.7

2.25

0.00013

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0449

Lipoprotein

3 of 17

1.61

1.64

0.0021

KW-0732

Signal

3 of 36

1.29

1.07

0.0084

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (22%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About