STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
comGDPutative competence protein ComGD; High confidence in function and specificity. (147 aa)    
Predicted Functional Partners:
llmg_2404
Conserved hypothetical protein.
  
  
 0.837
comGB
Putative competence protein ComGB; PF00482: Bacterial type II secretion system protein F domain, putative membrane protein; Conserved hypothetical protein.
  
  
 0.808
llmg_2403
Conserved hypothetical protein.
       0.800
comGC
Putative competence protein ComGC; Specificity unclear.
       0.800
comGA
Putative competence protein ComGA; PF00437: Type II/IV secretion system protein; Conserved hypothetical protein.
     
 0.797
llmg_2402
Hypothetical protein predicted by Glimmer.
       0.705
zitS
Zinc ABC transporter substrate binding protein; PF01297.7: Periplasmic solute binding protein family; High confidence in function and specificity; Belongs to the bacterial solute-binding protein 9 family.
       0.511
zitR
Transcriptional regulator of the zit operon; Zinc-responsive regulator that represses expression of the zit operon in the presence of zinc. Acts by binding two palindromic operator sites overlapping the -35 and -10 boxes of the zit promoter. Could be a sensitive sensor of intracellular zinc to efficiently respond to zinc variations in the environment.
       0.511
polC
DNA polymerase III alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
       0.487
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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