STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glnAGlnA protein; PF00120: Glutamine synthetase, catalytic domain, TIGR00653: glutamine synthetase, type I; High confidence in function and specificity. (446 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase, large subunit; PF01645: Conserved region in glutamate synthase; High confidence in function and specificity.
  
 
 0.987
glnR
Glutamine synthetase repressor; GLNR, MerR family transcriptional regulator; High confidence in function and specificity.
 
 
 0.973
glmS
Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
 
 
 0.970
carA
Carbamoyl-phosphate synthase small chain; High confidence in function and specificity; Belongs to the CarA family.
  
 
 0.964
gltD
TIGR01317: glutamate synthases, NADH/NADPH, small subunit; High confidence in function and specificity.
  
 
 0.961
carB
Carbamoyl-phosphate synthase, large subunit; Region start changed from 1046934 to 1046961 (-27 bases); Belongs to the CarB family.
  
 
 0.957
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.930
gadB
Glutamate decarboxylase; Converts internalized glutamate to GABA and increases the internal pH. Involved in glutamate-dependent acid resistance; Belongs to the group II decarboxylase family.
  
 
 0.926
arcC2
ArcC2 protein; Aspartate/glutamate/uridylate kinase, PF00696: Amino acid kinase family, TIGR00746: carbamate kinase; High confidence in function and specificity; Belongs to the carbamate kinase family.
     
 0.917
arcC1
ArcC1 protein; PF00696: Amino acid kinase family, TIGR00746: carbamate kinase; High confidence in function and specificity; Belongs to the carbamate kinase family.
     
 0.917
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.