STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mreCCell shape determining protein mreC; Involved in formation and maintenance of cell shape. (291 aa)    
Predicted Functional Partners:
pbp2B
Penicillin-binding protein 2B; High confidence in function and specificity.
 
 
 0.984
rodA
Rod shape-determining protein RodA; Cell cycle protein; High confidence in function and specificity; Belongs to the SEDS family.
 
  
 0.975
llmg_2508
Cell shape determining protein mreD; Region start changed from 2464405 to 2464456 (51 bases).
  
 
 0.956
pbp2A
Penicillin-binding protein 2a; PF00912: Transglycosylase; High confidence in function and specificity.
  
 
 0.943
ftsZ
Cell division protein ftsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.879
ftsA
Cell division protein ftsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
 
  
 0.875
pbp1B
Penicillin-binding protein 1B; High confidence in function and specificity.
  
 
 0.855
ezrA
Septation ring formation regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
     
 0.841
nah
Na+/H+ antiporter; Sodium/hydrogen exchanger family; High confidence in function and specificity.
 
   
 0.792
mapZ
Conserved hypothetical protein; Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning.
      
 0.759
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.