node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDM93268.1 | SDN82430.1 | SAMN04487951_101181 | SAMN04487951_108174 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.958 |
SDM93268.1 | SDN90106.1 | SAMN04487951_101181 | SAMN04487951_109131 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Belongs to the precorrin methyltransferase family. | 0.956 |
SDM93268.1 | SDO11795.1 | SAMN04487951_101181 | SAMN04487951_11371 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | uroporphyrin-III C-methyltransferase. | 0.953 |
SDM93268.1 | hemA | SAMN04487951_101181 | SAMN04487951_11183 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.715 |
SDM93268.1 | hemC | SAMN04487951_101181 | SAMN04487951_101182 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.998 |
SDM93268.1 | hemE | SAMN04487951_101181 | SAMN04487951_101268 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.945 |
SDM93268.1 | hemL | SAMN04487951_101181 | SAMN04487951_10115 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.765 |
SDN82394.1 | SDN82430.1 | SAMN04487951_108173 | SAMN04487951_108174 | Enhancing lycopene biosynthesis protein 2; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.739 |
SDN82394.1 | ppk | SAMN04487951_108173 | SAMN04487951_108175 | Enhancing lycopene biosynthesis protein 2; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.514 |
SDN82430.1 | SDM93268.1 | SAMN04487951_108174 | SAMN04487951_101181 | Porphobilinogen synthase; Belongs to the ALAD family. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.958 |
SDN82430.1 | SDN82394.1 | SAMN04487951_108174 | SAMN04487951_108173 | Porphobilinogen synthase; Belongs to the ALAD family. | Enhancing lycopene biosynthesis protein 2; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family. | 0.739 |
SDN82430.1 | SDN90106.1 | SAMN04487951_108174 | SAMN04487951_109131 | Porphobilinogen synthase; Belongs to the ALAD family. | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Belongs to the precorrin methyltransferase family. | 0.976 |
SDN82430.1 | SDO11795.1 | SAMN04487951_108174 | SAMN04487951_11371 | Porphobilinogen synthase; Belongs to the ALAD family. | uroporphyrin-III C-methyltransferase. | 0.976 |
SDN82430.1 | bioF | SAMN04487951_108174 | SAMN04487951_105133 | Porphobilinogen synthase; Belongs to the ALAD family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.753 |
SDN82430.1 | hemA | SAMN04487951_108174 | SAMN04487951_11183 | Porphobilinogen synthase; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.881 |
SDN82430.1 | hemC | SAMN04487951_108174 | SAMN04487951_101182 | Porphobilinogen synthase; Belongs to the ALAD family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.997 |
SDN82430.1 | hemE | SAMN04487951_108174 | SAMN04487951_101268 | Porphobilinogen synthase; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.786 |
SDN82430.1 | hemL | SAMN04487951_108174 | SAMN04487951_10115 | Porphobilinogen synthase; Belongs to the ALAD family. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.994 |
SDN82430.1 | ppk | SAMN04487951_108174 | SAMN04487951_108175 | Porphobilinogen synthase; Belongs to the ALAD family. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.736 |
SDN90106.1 | SDM93268.1 | SAMN04487951_109131 | SAMN04487951_101181 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Belongs to the precorrin methyltransferase family. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.956 |