jhhlp_007587 protein (Lomentospora prolificans)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

jhhlp_007587

Uncharacterized protein. (319 aa)

Predicted Functional Partners:

jhhlp_007817

0.987

jhhlp_004238

0.987

jhhlp_006034

0.984

jhhlp_001170

0.984

jhhlp_004042

0.983

jhhlp_004495

0.983

jhhlp_001410

0.983

jhhlp_008691

0.982

jhhlp_007110

0.982

jhhlp_007291

0.982

Your Current Organism:

Lomentospora prolificans

NCBI taxonomy Id: 41688
Other names: CBS 467.74, IMI 188615, L. prolificans, MUCL 18141, Scedosporium inflatum, Scedosporium prolificans

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
jhhlp_001170	jhhlp_001410	A0A2N3NHD5	A0A2N3NID1	Ribosomal_L23eN domain-containing protein.	Ribosomal_L14e domain-containing protein.	0.999
jhhlp_001170	jhhlp_004042	A0A2N3NHD5	A0A2N3NAK1	Ribosomal_L23eN domain-containing protein.	Uncharacterized protein.	0.999
jhhlp_001170	jhhlp_004238	A0A2N3NHD5	A0A2N3NB11	Ribosomal_L23eN domain-containing protein.	Uncharacterized protein.	0.988
jhhlp_001170	jhhlp_004495	A0A2N3NHD5	A0A2N3NBY2	Ribosomal_L23eN domain-containing protein.	Uncharacterized protein.	0.999
jhhlp_001170	jhhlp_006034	A0A2N3NHD5	A0A2N3N4S3	Ribosomal_L23eN domain-containing protein.	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.	0.999
jhhlp_001170	jhhlp_007110	A0A2N3NHD5	A0A2N3N1S4	Ribosomal_L23eN domain-containing protein.	Uncharacterized protein.	0.999
jhhlp_001170	jhhlp_007291	A0A2N3NHD5	A0A2N3N2A1	Ribosomal_L23eN domain-containing protein.	60S ribosomal protein L6; Belongs to the eukaryotic ribosomal protein eL6 family.	0.999
jhhlp_001170	jhhlp_007587	A0A2N3NHD5	A0A2N3N007	Ribosomal_L23eN domain-containing protein.	Uncharacterized protein.	0.984
jhhlp_001170	jhhlp_007817	A0A2N3NHD5	A0A2N3N0N4	Ribosomal_L23eN domain-containing protein.	Uncharacterized protein.	0.991
jhhlp_001170	jhhlp_008691	A0A2N3NHD5	A0A2N3MYR3	Ribosomal_L23eN domain-containing protein.	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL38 family.	0.999
jhhlp_001410	jhhlp_001170	A0A2N3NID1	A0A2N3NHD5	Ribosomal_L14e domain-containing protein.	Ribosomal_L23eN domain-containing protein.	0.999
jhhlp_001410	jhhlp_004042	A0A2N3NID1	A0A2N3NAK1	Ribosomal_L14e domain-containing protein.	Uncharacterized protein.	0.999
jhhlp_001410	jhhlp_004238	A0A2N3NID1	A0A2N3NB11	Ribosomal_L14e domain-containing protein.	Uncharacterized protein.	0.992
jhhlp_001410	jhhlp_004495	A0A2N3NID1	A0A2N3NBY2	Ribosomal_L14e domain-containing protein.	Uncharacterized protein.	0.999
jhhlp_001410	jhhlp_006034	A0A2N3NID1	A0A2N3N4S3	Ribosomal_L14e domain-containing protein.	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.	0.999
jhhlp_001410	jhhlp_007110	A0A2N3NID1	A0A2N3N1S4	Ribosomal_L14e domain-containing protein.	Uncharacterized protein.	0.999
jhhlp_001410	jhhlp_007291	A0A2N3NID1	A0A2N3N2A1	Ribosomal_L14e domain-containing protein.	60S ribosomal protein L6; Belongs to the eukaryotic ribosomal protein eL6 family.	0.999
jhhlp_001410	jhhlp_007587	A0A2N3NID1	A0A2N3N007	Ribosomal_L14e domain-containing protein.	Uncharacterized protein.	0.983
jhhlp_001410	jhhlp_007817	A0A2N3NID1	A0A2N3N0N4	Ribosomal_L14e domain-containing protein.	Uncharacterized protein.	0.989
jhhlp_001410	jhhlp_008691	A0A2N3NID1	A0A2N3MYR3	Ribosomal_L14e domain-containing protein.	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL38 family.	0.999

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Network Stats

number of nodes:

11

number of edges:

42

average node degree:

7.64

avg. local clustering coefficient:

0.708

expected number of edges:

13

PPI enrichment p-value:

1.09e-10

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0015288

Porin activity

4 of 19

2.0

2.05

6.74e-05

GO:0022857

Transmembrane transporter activity

5 of 322

0.87

0.47

0.0456

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019867

Outer membrane

3 of 60

1.38

0.67

0.0365

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7125

Mixed, incl. Clostripain family, and Integrin alpha (beta-propellor repeats).

5 of 12

2.3

3.92

1.17e-08

CL:7117

Mixed, incl. Outer membrane, and Quorum sensing

9 of 112

1.58

3.03

7.80e-11

CL:7128

Clostripain family, and Integrin alpha (beta-propellor repeats).

3 of 6

2.38

2.32

3.93e-05

CL:7248

TonB box, and OmpA family

4 of 23

1.92

2.27

1.40e-05

CL:7249

TonB box, and WD40-like Beta Propeller Repeat

3 of 18

1.9

1.61

0.00052

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02040

Flagellar assembly

3 of 49

1.47

0.81

0.0184

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0046930

Pore complex

3 of 8

2.25

1.83

0.00033

GOCC:0005576

Extracellular region

4 of 138

1.14

0.67

0.0218

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0732

Signal

8 of 384

1.0

1.02

2.54e-05

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF03415

Clostripain family

3 of 3

2.68

2.18

9.68e-05

PF00691

OmpA family

3 of 8

2.25

1.79

0.00040

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00060

Fibronectin type 3 domain

3 of 12

2.08

1.73

0.00041

SM00327

Von Willebrand factor (vWF) type A domain

3 of 17

1.93

1.63

0.00051

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