STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
jhhlp_007735ANK_REP_REGION domain-containing protein. (569 aa)    
Predicted Functional Partners:
jhhlp_008120
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.998
jhhlp_002564
3'-5' exonuclease domain-containing protein.
   
 0.996
jhhlp_000061
Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.
    
 0.995
jhhlp_006390
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.989
jhhlp_005704
Ubiquitin carboxyl-terminal hydrolase.
    
 0.986
jhhlp_001804
Ubiquitin carboxyl-terminal hydrolase.
    
 0.986
jhhlp_000136
Uncharacterized protein.
   
 0.982
jhhlp_005195
AAA_23 domain-containing protein.
    
 0.979
jhhlp_001638
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 0.979
jhhlp_008310
Ubiquitin-like domain-containing protein.
    
  0.943
Your Current Organism:
Lomentospora prolificans
NCBI taxonomy Id: 41688
Other names: CBS 467.74, IMI 188615, L. prolificans, MUCL 18141, Scedosporium inflatum, Scedosporium prolificans
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.