node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | jhhlp_000026 | A0A2N3NFI5 | A0A2N3NLC3 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA ligase. | 0.860 |
FEN1 | jhhlp_001375 | A0A2N3NFI5 | A0A2N3NHZ1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Endo/exonuclease/phosphatase domain-containing protein. | 0.994 |
FEN1 | jhhlp_001583 | A0A2N3NFI5 | A0A2N3NIM3 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.441 |
FEN1 | jhhlp_002064 | A0A2N3NFI5 | A0A2N3ND25 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA ligase. | 0.979 |
FEN1 | jhhlp_003034 | A0A2N3NFI5 | A0A2N3NFX7 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Poly [ADP-ribose] polymerase. | 0.889 |
FEN1 | jhhlp_003740 | A0A2N3NFI5 | A0A2N3N9K2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | SAP domain-containing protein. | 0.747 |
FEN1 | jhhlp_005779 | A0A2N3NFI5 | A0A2N3N425 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA ligase. | 0.976 |
FEN1 | jhhlp_006581 | A0A2N3NFI5 | A0A2N3N6A2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA_LIGASE_A3 domain-containing protein. | 0.801 |
FEN1 | jhhlp_007139 | A0A2N3NFI5 | A0A2N3N1U6 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | BRCT domain-containing protein. | 0.915 |
FEN1 | jhhlp_008637 | A0A2N3NFI5 | A0A2N3MYL0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase. | 0.994 |
jhhlp_000026 | FEN1 | A0A2N3NLC3 | A0A2N3NFI5 | DNA ligase. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.860 |
jhhlp_000026 | jhhlp_001375 | A0A2N3NLC3 | A0A2N3NHZ1 | DNA ligase. | Endo/exonuclease/phosphatase domain-containing protein. | 0.766 |
jhhlp_000026 | jhhlp_001583 | A0A2N3NLC3 | A0A2N3NIM3 | DNA ligase. | Uncharacterized protein. | 0.854 |
jhhlp_000026 | jhhlp_002064 | A0A2N3NLC3 | A0A2N3ND25 | DNA ligase. | DNA ligase. | 0.580 |
jhhlp_000026 | jhhlp_003034 | A0A2N3NLC3 | A0A2N3NFX7 | DNA ligase. | Poly [ADP-ribose] polymerase. | 0.625 |
jhhlp_000026 | jhhlp_003740 | A0A2N3NLC3 | A0A2N3N9K2 | DNA ligase. | SAP domain-containing protein. | 0.987 |
jhhlp_000026 | jhhlp_005779 | A0A2N3NLC3 | A0A2N3N425 | DNA ligase. | DNA ligase. | 0.589 |
jhhlp_000026 | jhhlp_007139 | A0A2N3NLC3 | A0A2N3N1U6 | DNA ligase. | BRCT domain-containing protein. | 0.878 |
jhhlp_000026 | jhhlp_008637 | A0A2N3NLC3 | A0A2N3MYL0 | DNA ligase. | DNA polymerase. | 0.722 |
jhhlp_001375 | FEN1 | A0A2N3NHZ1 | A0A2N3NFI5 | Endo/exonuclease/phosphatase domain-containing protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.994 |