STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
jhhlp_007422Uncharacterized protein. (683 aa)    
Predicted Functional Partners:
jhhlp_007311
Uncharacterized protein.
  
 
0.977
jhhlp_004493
Protein kinase domain-containing protein.
  
0.959
jhhlp_004015
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.955
jhhlp_007607
MRC1 domain-containing protein.
    
 0.938
jhhlp_007149
Protein kinase domain-containing protein.
  
0.933
jhhlp_002499
RFX-type winged-helix domain-containing protein.
    
 0.930
jhhlp_000061
Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.
    
 0.930
jhhlp_004442
BRCT domain-containing protein.
    
 0.915
jhhlp_007236
Rhodanese domain-containing protein.
   
 0.895
jhhlp_002327
Uncharacterized protein; Belongs to the cytochrome P450 family.
 
      0.838
Your Current Organism:
Lomentospora prolificans
NCBI taxonomy Id: 41688
Other names: CBS 467.74, IMI 188615, L. prolificans, MUCL 18141, Scedosporium inflatum, Scedosporium prolificans
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.