STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIM1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (1112 aa)    
Predicted Functional Partners:
jhhlp_005512
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
  
  
 0.864
jhhlp_003573
BRO1 domain-containing protein.
 
 
    0.863
jhhlp_001102
TPR_REGION domain-containing protein.
   
 0.804
jhhlp_002861
ATP-dependent Clp protease proteolytic subunit.
  
 
 0.769
jhhlp_001545
Uncharacterized protein.
 
 
 0.752
jhhlp_006272
SCP2 domain-containing protein.
   
 
 0.723
jhhlp_004385
AAA domain-containing protein.
  
 
 0.694
jhhlp_006167
Uncharacterized protein.
    
 0.672
jhhlp_003684
Uncharacterized protein.
    
 0.672
jhhlp_000205
Pex14_N domain-containing protein.
   
 0.666
Your Current Organism:
Lomentospora prolificans
NCBI taxonomy Id: 41688
Other names: CBS 467.74, IMI 188615, L. prolificans, MUCL 18141, Scedosporium inflatum, Scedosporium prolificans
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