jhhlp_004456 protein (Lomentospora prolificans)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

jhhlp_004456

Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (678 aa)

Predicted Functional Partners:

jhhlp_005299

0.805

jhhlp_004141

0.598

jhhlp_000448

0.571

jhhlp_001907

0.555

jhhlp_002599

0.555

jhhlp_003027

0.555

jhhlp_003335

0.555

jhhlp_000801

0.555

jhhlp_000964

0.527

jhhlp_001577

0.494

Your Current Organism:

Lomentospora prolificans

NCBI taxonomy Id: 41688
Other names: CBS 467.74, IMI 188615, L. prolificans, MUCL 18141, Scedosporium inflatum, Scedosporium prolificans

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
jhhlp_000448	jhhlp_000964	A0A2N3NKV7	A0A2N3NK11	Tryptophan synthase.	Pribosyltran domain-containing protein.	0.635
jhhlp_000448	jhhlp_004141	A0A2N3NKV7	A0A2N3NAS8	Tryptophan synthase.	N-acetyltransferase domain-containing protein; In the N-terminal section; belongs to the acetylglutamate kinase family.	0.703
jhhlp_000448	jhhlp_004456	A0A2N3NKV7	A0A2N3NBM4	Tryptophan synthase.	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	0.571
jhhlp_000801	jhhlp_004456	A0A2N3NJI3	A0A2N3NBM4	Fungal_trans domain-containing protein.	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	0.555
jhhlp_000964	jhhlp_000448	A0A2N3NK11	A0A2N3NKV7	Pribosyltran domain-containing protein.	Tryptophan synthase.	0.635
jhhlp_000964	jhhlp_004456	A0A2N3NK11	A0A2N3NBM4	Pribosyltran domain-containing protein.	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	0.527
jhhlp_001577	jhhlp_004141	A0A2N3NIK9	A0A2N3NAS8	Amino acid transporter.	N-acetyltransferase domain-containing protein; In the N-terminal section; belongs to the acetylglutamate kinase family.	0.431
jhhlp_001577	jhhlp_004456	A0A2N3NIK9	A0A2N3NBM4	Amino acid transporter.	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	0.494
jhhlp_001577	jhhlp_005299	A0A2N3NIK9	A0A2N3N7E0	Amino acid transporter.	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	0.484
jhhlp_001907	jhhlp_004456	A0A2N3NCM9	A0A2N3NBM4	Zn(2)-C6 fungal-type domain-containing protein.	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	0.555
jhhlp_002599	jhhlp_004456	A0A2N3NEQ2	A0A2N3NBM4	Zn(2)-C6 fungal-type domain-containing protein.	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	0.555
jhhlp_003027	jhhlp_004456	A0A2N3NFS1	A0A2N3NBM4	Fungal_trans domain-containing protein.	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	0.555
jhhlp_003335	jhhlp_004456	A0A2N3NGJ4	A0A2N3NBM4	Zn(2)-C6 fungal-type domain-containing protein.	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	0.555
jhhlp_004141	jhhlp_000448	A0A2N3NAS8	A0A2N3NKV7	N-acetyltransferase domain-containing protein; In the N-terminal section; belongs to the acetylglutamate kinase family.	Tryptophan synthase.	0.703
jhhlp_004141	jhhlp_001577	A0A2N3NAS8	A0A2N3NIK9	N-acetyltransferase domain-containing protein; In the N-terminal section; belongs to the acetylglutamate kinase family.	Amino acid transporter.	0.431
jhhlp_004141	jhhlp_004456	A0A2N3NAS8	A0A2N3NBM4	N-acetyltransferase domain-containing protein; In the N-terminal section; belongs to the acetylglutamate kinase family.	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	0.598
jhhlp_004141	jhhlp_005299	A0A2N3NAS8	A0A2N3N7E0	N-acetyltransferase domain-containing protein; In the N-terminal section; belongs to the acetylglutamate kinase family.	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.	0.543
jhhlp_004456	jhhlp_000448	A0A2N3NBM4	A0A2N3NKV7	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	Tryptophan synthase.	0.571
jhhlp_004456	jhhlp_000801	A0A2N3NBM4	A0A2N3NJI3	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	Fungal_trans domain-containing protein.	0.555
jhhlp_004456	jhhlp_000964	A0A2N3NBM4	A0A2N3NK11	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	Pribosyltran domain-containing protein.	0.527

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

22

average node degree:

4

avg. local clustering coefficient:

0.83

expected number of edges:

15

PPI enrichment p-value:

0.0417

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 114

1.55

3.35

2.24e-14

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

9 of 55

1.78

4.0

1.47e-12

GO:0019843

rRNA binding

7 of 42

1.78

3.3

2.02e-09

GO:0003723

RNA binding

8 of 121

1.38

2.08

2.56e-08

GO:0000049

tRNA binding

4 of 28

1.72

1.74

0.00013

GO:0003676

Nucleic acid binding

9 of 504

0.81

0.76

5.43e-05

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

9 of 63

1.72

3.82

8.73e-13

GO:0015935

Small ribosomal subunit

3 of 6

2.26

2.33

3.03e-05

GO:0005622

Intracellular anatomical structure

11 of 1355

0.47

0.41

0.00014

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:23342046

(2013) The genome sequences of Cellulomonas fimi and Cellvibrio gilvus reveal the cellulolytic strategies of two facultative anaerobes, transfer of Cellvibrio gilvus to the genus Cellulomonas, and proposal of Cellulomonas gilvus sp. nov.

3 of 32

1.53

0.95

0.0091

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:162

Ribosome

9 of 43

1.88

4.66

9.85e-14

CL:166

rRNA-binding

7 of 28

1.96

4.23

3.68e-11

CL:169

rRNA-binding

5 of 15

2.08

3.46

3.66e-08

CL:133

Translation, and Protein export

11 of 136

1.47

2.97

9.85e-14

CL:173

mRNA binding, and rRNA-binding

3 of 6

2.26

2.21

5.49e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

sde03010

Ribosome

9 of 53

1.79

4.26

1.58e-13

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

7 of 52

1.69

2.92

9.28e-09

GOCC:0022626

Cytosolic ribosome

5 of 29

1.8

2.55

1.03e-06

GOCC:0044391

Ribosomal subunit

5 of 33

1.74

2.44

1.23e-06

GOCC:0022627

Cytosolic small ribosomal subunit

3 of 13

1.92

1.77

0.00024

GOCC:0043229

Intracellular organelle

9 of 280

1.07

1.29

3.19e-07

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

9 of 55

1.78

4.11

4.44e-13

KW-0699

rRNA-binding

7 of 39

1.82

3.57

3.82e-10

KW-0820

tRNA-binding

3 of 19

1.76

1.43

0.0010

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