node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | jhhlp_000342 | A0A2N3NFI5 | A0A2N3NKT5 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). | 0.958 |
FEN1 | jhhlp_000354 | A0A2N3NFI5 | A0A2N3NKP4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.899 |
FEN1 | jhhlp_001321 | A0A2N3NFI5 | A0A2N3NHW0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA_MISMATCH_REPAIR_2 domain-containing protein. | 0.879 |
FEN1 | jhhlp_003343 | A0A2N3NFI5 | A0A2N3NGM6 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.846 |
FEN1 | jhhlp_005899 | A0A2N3NFI5 | A0A2N3N4E2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA_mis_repair domain-containing protein. | 0.874 |
FEN1 | jhhlp_006474 | A0A2N3NFI5 | A0A2N3N615 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA_MISMATCH_REPAIR_2 domain-containing protein. | 0.754 |
FEN1 | jhhlp_007063 | A0A2N3NFI5 | A0A2N3N1L2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). | 0.874 |
FEN1 | jhhlp_007069 | A0A2N3NFI5 | A0A2N3N1N8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA_MISMATCH_REPAIR_2 domain-containing protein. | 0.777 |
jhhlp_000342 | FEN1 | A0A2N3NKT5 | A0A2N3NFI5 | DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.958 |
jhhlp_000342 | jhhlp_000354 | A0A2N3NKT5 | A0A2N3NKP4 | DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). | Uncharacterized protein. | 0.990 |
jhhlp_000342 | jhhlp_003343 | A0A2N3NKT5 | A0A2N3NGM6 | DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). | Uncharacterized protein. | 0.996 |
jhhlp_000342 | jhhlp_005899 | A0A2N3NKT5 | A0A2N3N4E2 | DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). | DNA_mis_repair domain-containing protein. | 0.996 |
jhhlp_000342 | jhhlp_006474 | A0A2N3NKT5 | A0A2N3N615 | DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). | DNA_MISMATCH_REPAIR_2 domain-containing protein. | 0.411 |
jhhlp_000342 | jhhlp_007063 | A0A2N3NKT5 | A0A2N3N1L2 | DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). | 0.999 |
jhhlp_000342 | jhhlp_007069 | A0A2N3NKT5 | A0A2N3N1N8 | DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). | DNA_MISMATCH_REPAIR_2 domain-containing protein. | 0.536 |
jhhlp_000354 | FEN1 | A0A2N3NKP4 | A0A2N3NFI5 | Uncharacterized protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.899 |
jhhlp_000354 | jhhlp_000342 | A0A2N3NKP4 | A0A2N3NKT5 | Uncharacterized protein. | DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). | 0.990 |
jhhlp_000354 | jhhlp_001321 | A0A2N3NKP4 | A0A2N3NHW0 | Uncharacterized protein. | DNA_MISMATCH_REPAIR_2 domain-containing protein. | 0.970 |
jhhlp_000354 | jhhlp_003343 | A0A2N3NKP4 | A0A2N3NGM6 | Uncharacterized protein. | Uncharacterized protein. | 0.985 |
jhhlp_000354 | jhhlp_005899 | A0A2N3NKP4 | A0A2N3N4E2 | Uncharacterized protein. | DNA_mis_repair domain-containing protein. | 0.991 |