jhhlp_000064 protein (Lomentospora prolificans)

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Score

jhhlp_000064

POLAc domain-containing protein. (1141 aa)

Predicted Functional Partners:

jhhlp_000306

0.925

jhhlp_008120

0.759

jhhlp_005195

0.703

FEN1

0.691

jhhlp_003034

0.681

jhhlp_003184

0.671

jhhlp_002238

0.663

jhhlp_000210

0.658

jhhlp_001209

0.652

jhhlp_004639

0.643

Your Current Organism:

Lomentospora prolificans

NCBI taxonomy Id: 41688
Other names: CBS 467.74, IMI 188615, L. prolificans, MUCL 18141, Scedosporium inflatum, Scedosporium prolificans

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FEN1	jhhlp_000064	A0A2N3NFI5	A0A2N3NLH3	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	POLAc domain-containing protein.	0.691
FEN1	jhhlp_000210	A0A2N3NFI5	A0A2N3NKA7	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.856
FEN1	jhhlp_003034	A0A2N3NFI5	A0A2N3NFX7	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Poly [ADP-ribose] polymerase.	0.889
FEN1	jhhlp_003184	A0A2N3NFI5	A0A2N3NGA2	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	FPG_CAT domain-containing protein.	0.651
FEN1	jhhlp_005195	A0A2N3NFI5	A0A2N3N796	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	AAA_23 domain-containing protein.	0.959
FEN1	jhhlp_008120	A0A2N3NFI5	A0A2N3MZL6	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.984
jhhlp_000064	FEN1	A0A2N3NLH3	A0A2N3NFI5	POLAc domain-containing protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.691
jhhlp_000064	jhhlp_000210	A0A2N3NLH3	A0A2N3NKA7	POLAc domain-containing protein.	Uncharacterized protein.	0.658
jhhlp_000064	jhhlp_000306	A0A2N3NLH3	A0A2N3NKJ0	POLAc domain-containing protein.	AA_TRNA_LIGASE_II domain-containing protein.	0.925
jhhlp_000064	jhhlp_001209	A0A2N3NLH3	A0A2N3NHK5	POLAc domain-containing protein.	Uncharacterized protein.	0.652
jhhlp_000064	jhhlp_002238	A0A2N3NLH3	A0A2N3NDE2	POLAc domain-containing protein.	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.663
jhhlp_000064	jhhlp_003034	A0A2N3NLH3	A0A2N3NFX7	POLAc domain-containing protein.	Poly [ADP-ribose] polymerase.	0.681
jhhlp_000064	jhhlp_003184	A0A2N3NLH3	A0A2N3NGA2	POLAc domain-containing protein.	FPG_CAT domain-containing protein.	0.671
jhhlp_000064	jhhlp_004639	A0A2N3NLH3	A0A2N3NC39	POLAc domain-containing protein.	Triosephosphate isomerase.	0.643
jhhlp_000064	jhhlp_005195	A0A2N3NLH3	A0A2N3N796	POLAc domain-containing protein.	AAA_23 domain-containing protein.	0.703
jhhlp_000064	jhhlp_008120	A0A2N3NLH3	A0A2N3MZL6	POLAc domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.759
jhhlp_000210	FEN1	A0A2N3NKA7	A0A2N3NFI5	Uncharacterized protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.856
jhhlp_000210	jhhlp_000064	A0A2N3NKA7	A0A2N3NLH3	Uncharacterized protein.	POLAc domain-containing protein.	0.658
jhhlp_000210	jhhlp_002238	A0A2N3NKA7	A0A2N3NDE2	Uncharacterized protein.	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.812
jhhlp_000210	jhhlp_003034	A0A2N3NKA7	A0A2N3NFX7	Uncharacterized protein.	Poly [ADP-ribose] polymerase.	0.747