STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEC42479.1methylmalonyl-CoA mutase. (722 aa)    
Predicted Functional Partners:
SEE16830.1
succinyl-CoA:acetate CoA-transferase.
 
 
 0.993
SEE14256.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
 
  
 0.977
SEE66249.1
Urea carboxylase.
  
 
 0.967
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.953
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.949
SEE74131.1
Non-ribosomal peptide synthase domain TIGR01720/amino acid adenylation domain-containing protein.
    
 0.945
SEB53808.1
Indolepyruvate ferredoxin oxidoreductase.
    
 0.941
SED03054.1
Indolepyruvate ferredoxin oxidoreductase.
    
 0.941
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
    
 0.941
SEB73030.1
Citrate synthase.
    
 0.917
Your Current Organism:
Paraburkholderia caballeronis
NCBI taxonomy Id: 416943
Other names: Burkholderia caballeronis, Burkholderia caballeronis Martinez et al. 2014, Burkholderia sp. TNe-834, Burkholderia sp. TNe-835, Burkholderia sp. TNe-841, Burkholderia sp. TNe-8411, Burkholderia sp. TNe-8641, Burkholderia sp. TNe-8683, Burkholderia sp. TNe-869, Burkholderia sp. TNe-878, CIP 110324, LMG 26416, LMG:26416, P. caballeronis, Paraburkholderia caballeronis (Martinez et al. 2014) Sawana et al. 2017, strain TNe-841
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