STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEE69492.1uroporphyrinogen-III C-methyltransferase. (253 aa)    
Predicted Functional Partners:
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.991
SEE30886.1
Precorrin-2/cobalt-factor-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A.
 
 
 0.969
SEC79866.1
uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
  
  
 
0.953
SEB55788.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.936
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
    
 0.920
SEE30847.1
Precorrin-3 methyltransferase.
 
 0.903
SEE69597.1
Sulfite reductase (NADPH) alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
 
  
 0.896
SEC80006.1
Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite.
 
  
 0.864
SEE80362.1
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase.
 
  
 0.845
hemL
Glutamate-1-semialdehyde 2,1-aminomutase.
 
  
 0.823
Your Current Organism:
Paraburkholderia caballeronis
NCBI taxonomy Id: 416943
Other names: Burkholderia caballeronis, Burkholderia caballeronis Martinez et al. 2014, Burkholderia sp. TNe-834, Burkholderia sp. TNe-835, Burkholderia sp. TNe-841, Burkholderia sp. TNe-8411, Burkholderia sp. TNe-8641, Burkholderia sp. TNe-8683, Burkholderia sp. TNe-869, Burkholderia sp. TNe-878, CIP 110324, LMG 26416, LMG:26416, P. caballeronis, Paraburkholderia caballeronis (Martinez et al. 2014) Sawana et al. 2017, strain TNe-841
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