STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CA982_19165tRNA-Ile; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)    
Predicted Functional Partners:
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.917
OUC76259.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.732
OUC78811.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.715
gyrB
DNA topoisomerase (ATP-hydrolyzing) subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP [...]
     
 0.690
OUC76994.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0232 family.
 
     0.682
OUC78818.1
Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.605
OUC79732.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.583
recF
DNA replication/repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
     
 0.569
OUC77112.1
dUTPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.534
OUC80864.1
Decaprenyl-phosphate phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UbiA prenyltransferase family.
  
 
 0.529
Your Current Organism:
Gordonia lacunae
NCBI taxonomy Id: 417102
Other names: DSM 45085, G. lacunae, Gordonia lacunae le Roes et al. 2009, JCM 14873, NRRL B-24551, strain BS2
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.