STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDJ52435.12,3-dihydroxybenzoate-AMP ligase. (547 aa)    
Predicted Functional Partners:
SDJ52394.1
Bifunctional isochorismate lyase / aryl carrier protein.
 
 0.999
SDJ52419.1
Bifunctional isochorismate lyase / aryl carrier protein.
 
 0.999
SDJ52559.1
Nonribosomal peptide synthetase DhbF.
 
 
0.996
SDJ52455.1
Isochorismate synthase.
 
 
 0.994
SDJ52471.1
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 0.973
SDJ52383.1
Enterobactin synthetase component F.
 
 0.959
SDJ52535.1
MbtH protein.
 
  
 0.950
SDL32046.1
Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.923
trpE
Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]
 
 
 0.879
SDK05209.1
Acyl transferase domain-containing protein.
  
 0.863
Your Current Organism:
Streptomyces indicus
NCBI taxonomy Id: 417292
Other names: CGMCC 4.5727, DSM 42001, S. indicus, Streptomyces indicus Luo et al. 2011, Streptomyces sp. IH32-1, strain IH32-1
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