STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (396 aa)    
Predicted Functional Partners:
SDK42113.1
Nicotinate-nucleotide pyrophosphorylase (carboxylating); Belongs to the NadC/ModD family.
 
 
 0.999
SDK42139.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 
 0.999
SDJ38250.1
Aspartate dehydrogenase.
    
 0.926
SDK32435.1
8-oxo-dGTP diphosphatase; Belongs to the Nudix hydrolase family.
  
  
 0.810
SDJ95570.1
Nicotinamide mononucleotide transporter.
  
  
 0.800
SDJ87001.1
Nicotinamide mononucleotide transporter.
  
  
 0.800
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
    0.792
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
  
   
 0.716
hisB
Imidazoleglycerol-phosphate dehydratase.
     
 0.703
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.691
Your Current Organism:
Streptomyces indicus
NCBI taxonomy Id: 417292
Other names: CGMCC 4.5727, DSM 42001, S. indicus, Streptomyces indicus Luo et al. 2011, Streptomyces sp. IH32-1, strain IH32-1
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