node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDJ90093.1 | SDK09233.1 | SAMN05421806_103215 | SAMN05421806_104397 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Belongs to the precorrin methyltransferase family. | Glutamate synthase (NADH) large subunit. | 0.886 |
SDJ90093.1 | SDK68914.1 | SAMN05421806_103215 | SAMN05421806_110144 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Belongs to the precorrin methyltransferase family. | uroporphyrinogen-III synthase. | 0.983 |
SDJ90093.1 | SDL34708.1 | SAMN05421806_103215 | SAMN05421806_12918 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen III methyltransferase / synthase. | 0.998 |
SDJ90093.1 | hemC | SAMN05421806_103215 | SAMN05421806_12917 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Belongs to the precorrin methyltransferase family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.998 |
SDJ90093.1 | hemE | SAMN05421806_103215 | SAMN05421806_10660 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.954 |
SDJ90093.1 | hemH | SAMN05421806_103215 | SAMN05421806_106157 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Belongs to the precorrin methyltransferase family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.549 |
SDK04842.1 | SDK61812.1 | SAMN05421806_104197 | SAMN05421806_109158 | Phytoene dehydrogenase-related protein. | Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.511 |
SDK04842.1 | SDK68914.1 | SAMN05421806_104197 | SAMN05421806_110144 | Phytoene dehydrogenase-related protein. | uroporphyrinogen-III synthase. | 0.451 |
SDK04842.1 | SDL34708.1 | SAMN05421806_104197 | SAMN05421806_12918 | Phytoene dehydrogenase-related protein. | Uroporphyrinogen III methyltransferase / synthase. | 0.531 |
SDK04842.1 | hemE | SAMN05421806_104197 | SAMN05421806_10660 | Phytoene dehydrogenase-related protein. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.882 |
SDK04842.1 | hemH | SAMN05421806_104197 | SAMN05421806_106157 | Phytoene dehydrogenase-related protein. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.835 |
SDK09233.1 | SDJ90093.1 | SAMN05421806_104397 | SAMN05421806_103215 | Glutamate synthase (NADH) large subunit. | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Belongs to the precorrin methyltransferase family. | 0.886 |
SDK09233.1 | SDK61812.1 | SAMN05421806_104397 | SAMN05421806_109158 | Glutamate synthase (NADH) large subunit. | Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.693 |
SDK09233.1 | SDL34708.1 | SAMN05421806_104397 | SAMN05421806_12918 | Glutamate synthase (NADH) large subunit. | Uroporphyrinogen III methyltransferase / synthase. | 0.706 |
SDK09233.1 | hemE | SAMN05421806_104397 | SAMN05421806_10660 | Glutamate synthase (NADH) large subunit. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.927 |
SDK28604.1 | SDK61812.1 | SAMN05421806_10654 | SAMN05421806_109158 | Oxygen-dependent protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.889 |
SDK28604.1 | SDK68914.1 | SAMN05421806_10654 | SAMN05421806_110144 | Oxygen-dependent protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | uroporphyrinogen-III synthase. | 0.451 |
SDK28604.1 | SDL34708.1 | SAMN05421806_10654 | SAMN05421806_12918 | Oxygen-dependent protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Uroporphyrinogen III methyltransferase / synthase. | 0.585 |
SDK28604.1 | hemC | SAMN05421806_10654 | SAMN05421806_12917 | Oxygen-dependent protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.592 |
SDK28604.1 | hemE | SAMN05421806_10654 | SAMN05421806_10660 | Oxygen-dependent protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.997 |