STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDK42201.1L-threonine aldolase. (423 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
 0.949
SDJ77350.1
L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
   
 0.930
SDL17401.1
L-threonine synthase.
   
 0.921
SDK40098.1
Threonine dehydratase.
   
 
 0.915
kbl
2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
     
 0.914
coaX
Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
       0.757
SDK42113.1
Nicotinate-nucleotide pyrophosphorylase (carboxylating); Belongs to the NadC/ModD family.
       0.757
SDK42139.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
       0.757
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
       0.757
SDK42186.1
Predicted oxidoreductase, contains short-chain dehydrogenase (SDR) and DUF2520 domains.
       0.757
Your Current Organism:
Streptomyces indicus
NCBI taxonomy Id: 417292
Other names: CGMCC 4.5727, DSM 42001, S. indicus, Streptomyces indicus Luo et al. 2011, Streptomyces sp. IH32-1, strain IH32-1
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