| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB78092.1 | KXB81946.1 | HMPREF1860_01135 | HMPREF1860_00040 | KEGG: tfo:BFO_2574 5.6e-16 hypothetical protein; K02372 3R-hydroxymyristoyl ACP dehydrase; Psort location: Cytoplasmic, score: 8.96. | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.789 |
| KXB78092.1 | lpxC | HMPREF1860_01135 | HMPREF1860_00041 | KEGG: tfo:BFO_2574 5.6e-16 hypothetical protein; K02372 3R-hydroxymyristoyl ACP dehydrase; Psort location: Cytoplasmic, score: 8.96. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.645 |
| KXB78092.1 | lpxD | HMPREF1860_01135 | HMPREF1860_00042 | KEGG: tfo:BFO_2574 5.6e-16 hypothetical protein; K02372 3R-hydroxymyristoyl ACP dehydrase; Psort location: Cytoplasmic, score: 8.96. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.414 |
| KXB78793.1 | KXB79145.1 | HMPREF1860_00838 | HMPREF1860_00689 | KEGG: pmz:HMPREF0659_A5655 2.0e-139 putative arabinose 5-phosphate isomerase; K06041 arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.739 |
| KXB78793.1 | KXB81946.1 | HMPREF1860_00838 | HMPREF1860_00040 | KEGG: pmz:HMPREF0659_A5655 2.0e-139 putative arabinose 5-phosphate isomerase; K06041 arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.753 |
| KXB78793.1 | kdsB | HMPREF1860_00838 | HMPREF1860_00923 | KEGG: pmz:HMPREF0659_A5655 2.0e-139 putative arabinose 5-phosphate isomerase; K06041 arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.876 |
| KXB78793.1 | lpxC | HMPREF1860_00838 | HMPREF1860_00041 | KEGG: pmz:HMPREF0659_A5655 2.0e-139 putative arabinose 5-phosphate isomerase; K06041 arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.657 |
| KXB78793.1 | lpxD | HMPREF1860_00838 | HMPREF1860_00042 | KEGG: pmz:HMPREF0659_A5655 2.0e-139 putative arabinose 5-phosphate isomerase; K06041 arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.697 |
| KXB78793.1 | lpxK | HMPREF1860_00838 | HMPREF1860_02159 | KEGG: pmz:HMPREF0659_A5655 2.0e-139 putative arabinose 5-phosphate isomerase; K06041 arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.846 |
| KXB79145.1 | KXB78793.1 | HMPREF1860_00689 | HMPREF1860_00838 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | KEGG: pmz:HMPREF0659_A5655 2.0e-139 putative arabinose 5-phosphate isomerase; K06041 arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.739 |
| KXB79145.1 | KXB81946.1 | HMPREF1860_00689 | HMPREF1860_00040 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.976 |
| KXB79145.1 | kdsB | HMPREF1860_00689 | HMPREF1860_00923 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.772 |
| KXB79145.1 | lpxC | HMPREF1860_00689 | HMPREF1860_00041 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.835 |
| KXB79145.1 | lpxD | HMPREF1860_00689 | HMPREF1860_00042 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.947 |
| KXB79145.1 | lpxK | HMPREF1860_00689 | HMPREF1860_02159 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.944 |
| KXB81944.1 | KXB81946.1 | HMPREF1860_00038 | HMPREF1860_00040 | Transglycosylase; KEGG: pdn:HMPREF9137_0007 0. transglycosylase; K05366 penicillin-binding protein 1A; Psort location: CytoplasmicMembrane, score: 9.82. | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.761 |
| KXB81944.1 | lpxC | HMPREF1860_00038 | HMPREF1860_00041 | Transglycosylase; KEGG: pdn:HMPREF9137_0007 0. transglycosylase; K05366 penicillin-binding protein 1A; Psort location: CytoplasmicMembrane, score: 9.82. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.736 |
| KXB81944.1 | lpxD | HMPREF1860_00038 | HMPREF1860_00042 | Transglycosylase; KEGG: pdn:HMPREF9137_0007 0. transglycosylase; K05366 penicillin-binding protein 1A; Psort location: CytoplasmicMembrane, score: 9.82. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.731 |
| KXB81944.1 | miaA | HMPREF1860_00038 | HMPREF1860_00039 | Transglycosylase; KEGG: pdn:HMPREF9137_0007 0. transglycosylase; K05366 penicillin-binding protein 1A; Psort location: CytoplasmicMembrane, score: 9.82. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.761 |
| KXB81946.1 | KXB78092.1 | HMPREF1860_00040 | HMPREF1860_01135 | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | KEGG: tfo:BFO_2574 5.6e-16 hypothetical protein; K02372 3R-hydroxymyristoyl ACP dehydrase; Psort location: Cytoplasmic, score: 8.96. | 0.789 |